Nikki Cox

Cox began her career at the age of four, when she appeared as a dancer in several ballet productions and TV specials. She began acting at the age of ten, making appearances in several movies and guest-starring on shows such as Baywatch, Star Trek: The Next Generation, Mama's Family, Eerie, Indiana, and Blossom. She also appeared in General Hospital from 1993 to 1995, and had a recurring role on the Saturday morning program California Dreams.

Her appearances on various TV shows led to her first prime-time role as Tiffany Malloy on the sitcom Unhappily Ever After, which ran on The WB from 1995 to 1999 for a total of five seasons. Her brother Matthew guest-starred on a handful of episodes, including one where he wore a "Ghostface" mask (the type of mask featured in Scream).

After Unhappily Ever After was cancelled (she appeared in all 100 episodes), Cox went on to portray Taylor Clayton, a former call-girl turned social worker on the ABC television sitcom The Norm Show which lasted for three seasons (she appeared in 27 of its 54 episodes). Next she starred as Nikki White in Nikki, another sitcom vehicle that lasted for two seasons on The WB (2000–2002).

The most successful show Cox co-starred in following her time on Unhappily Ever After was on the NBC TV drama Las Vegas from 2003 to 2007 for a total of four seasons. She played Mary Connell for 88 episodes. However, Cox would not appear on the fifth and final season of the show. On May 20 and 23, 2005, her Las Vegas character crossed over to NBC's soap opera Passions to coincide with the arrival of two new characters introduced on Las Vegas.

In 2006, she became the spokesmodel for the online gaming website Sportsbook.com. In 2009, she provided the voice of Jenna in Leisure Suit Larry: Box Office Bust. That same year, she also appeared in Lonely Street, a comedy, starring Robert Patrick, Jay Mohr, Ernie Hudson, and Lindsay Price. In 2016, Cox was nominated as the sole writer for Mohr's album Happy. And A Lot for the Grammy Award for Best Comedy Album at the 58th Annual Grammy Awards.