Wilson Cruz

Cruz was born in Brooklyn, New York, to parents born in Puerto Rico. His family eventually moved to Rialto, California, where he attended Eisenhower High School, graduating in 1991. At age 19, Cruz came out to his parents as gay, first to his mother and then to his father. While his mother was initially hurt and shocked, she eventually accepted the news. His father, however, threw him out of the house, and Cruz spent the next few months living in his car and at the homes of friends. He later reconciled with his father.Cruz went to Hollywood to seek work as an actor, intending to be open about his sexuality from the beginning of his career. In 1994, he was cast as Enrique "Rickie" Vasquez, a troubled, gay teen, in the short-lived, critically acclaimed cult classic TV series My So-Called Life. This made Cruz the first openly gay actor to play an openly gay character in a leading role in an American television series.

Following My So-Called Life's cancellation, Cruz went on to play J. Edgar Hoover's servant Joaquin in Oliver Stone's film Nixon and had a small role in the television movie On Seventh Avenue. In 1996, he appeared with David Arquette as Mikey in Johns, about the day-to-day struggles of male prostitutes. In 2000, he played Victor in the final season of Party of Five. He also had a recurring role as Rafael de la Cruz on the series, Raising the Bar.

Cruz's other acting credits include the films Joyride (1996), All Over Me (1997), Supernova (2000), Party Monster (2003), Margaret Cho's Bam Bam and Celeste (2005), Coffee Date (2007), and He's Just Not That Into You (2009); the television film The Perfect Pitch (2002); and guest appearances on the series Great Scott!, Sister, Sister, ER, Ally McBeal, The West Wing, Noah's Arc, and Grey's Anatomy. Cruz starred as Adrian in the film The Ode (2007), based on the novel Ode to Lata by Ghalib Shiraz Dhalla.

He also appeared/starred in the 2009 movie The People I've Slept With. He plays the best friend of a promiscuous woman who tries to find out who got her pregnant so that she can get married.

Since 2017, Cruz has portrayed Dr. Hugh Culber on the science fiction series Star Trek: Discovery.

Since 2020, Cruz has been a recurring guest on 25 Words or Less.

In 2023, Cruz became the new chair of the board of directors for GLSEN.