Lisa Palfrey

Palfrey was born in Wales on 9 February 1967, her mother is Eiry Palfrey, an actress and author. She attended Ysgol Gyfun Rhydfelen, a Welsh-medium secondary school near Pontypridd.Palfrey started acting at the age of 20 when she played the role of 15-year-old girl, Jane Sanderson, in the BBC One television series The District Nurse. Her first major role was in the film The Englishman Who Went Up a Hill But Came Down a Mountain. She has gone on to star in the cult film House of America, and appeared as Melanie Collier in the medical drama television series Casualty as well as Inspector Tracey McAndrew in the third series of the police procedural television series Line of Duty. She played the role of Rhiannedd Frost in the Welsh soap opera Pobol y Cwm.

Palfrey has performed in a number of plays, including the original production of David Eldridge's Festen, The Iceman Cometh, Under The Blue Sky, and Tom Wells's The Kitchen Sink.

In 2019, Palfrey played the role of Cynthia in the Netflix original series Sex Education.

In 2020, Palfrey played the role of government minister Eleanor James in the Sky One original television drama series COBRA, written by Ben Richards and starring Robert Carlyle as British Prime Minister Robert Sutherland. She played the part of Pam Green in the BBC Drama Chloe in 2022. In 2023 she filmed the BBC television feature Men Up, about the first clinical trials for the drug Viagra that took place in Swansea in 1994.