Jeremy Piven

Piven was born in Manhattan and raised in a Reconstructionist Jewish family of Ukrainian Jewish descent.

His parents are Byrne Piven (1929–2002) and Joyce Hiller Piven (née Goldstein), both of whom were actors and drama teachers. His elder sister is director Shira Piven, whom he has described as one of his first acting teachers; his brother-in-law is director Adam McKay.

Piven grew up in Evanston, Illinois, and graduated from Evanston Township High School. As a teenager, he attended Harand Theater Camp in Elkhart Lake, Wisconsin, where he played Bernardo in West Side Story. In Illinois, he trained at Piven Theatre Workshop, founded by his parents. He also attended Drake University in Des Moines, Iowa, where he departed after his sophomore year to attend New York University's Tisch School of the Arts. He left Tisch during his senior year to pursue his acting career and is an alumnus of the Pi Kappa Alpha fraternity. He spent a semester at the National Theater Institute at the Eugene O'Neill Theater Center in Waterford, Connecticut.

He has appeared in several films with John Cusack, who is also from Evanston and is a fellow alumnus of the Piven Theatre Workshop (as are Cusack's sisters Joan and Ann). Piven and Cusack once shared an apartment and have been friends since high school.One of Piven's early roles was Spike in Lucas (1986). His first important role came in 1992 when he became a regular cast member on HBO's The Larry Sanders Show, where he played head writer Jerry. He left the show in the second season after growing tired of the role, because his character was not given much of a background.

In 1993, he portrayed George Costanza on the show-within-a-show scene in the two-part Seinfeld episode "The Pilot". He was a supporting cast member on the last three seasons of the sitcom Ellen, where he played Ellen's cousin Spence. He also starred in and produced the short-lived ABC dramedy series Cupid, and voiced Elongated Man in three episodes of Justice League Unlimited.

Beginning in 2004, Piven achieved significant success as the fast-talking, acerbic Hollywood agent Ari Gold in the HBO series Entourage. He received Emmy nominations for Best Supporting Actor for four straight years, from 2005 to 2008, and won the award in 2006, 2007 and 2008. He also received Golden Globe nominations for the role from 2005 to 2010, and won in 2008.

Piven has appeared in numerous films, including Judgment Night, Grosse Pointe Blank, Singles, Very Bad Things, The Family Man, Black Hawk Down, The Kingdom, Heat, PCU, Old School, Rock N Rolla, Serendipity, Smokin' Aces, and Runaway Jury. He has also made cameo appearances in Rush Hour 2 and the U.S. release of Cars.

In 2007, Piven appeared in the video for "Drivin' Me Wild", the third single from rapper Common's seventh album, Finding Forever. The two were co-stars in Smokin' Aces and appeared together when Piven hosted SNL in January 2007.

Piven appeared in the first Broadway revival of David Mamet's Speed-the-Plow. The production began preview performances on October 3, 2008, and opened on October 23, 2008; the play was due to run through February 22, 2009. After Piven missed several performances, on December 17, 2008, Piven's representation announced that he had been suffering from hydrargyria, and would be ending his run in the play effective immediately. Mamet joked that Piven was leaving the play "to pursue a career as a thermometer." On September 1, 2009, Piven, in a guest appearance on the Late Show with David Letterman, explained that he had given up red meat and poultry, and had been getting all of his protein from fish for the past 20 years.

On August 3, 2009, Piven guest hosted the WWE Raw wrestling program. In August 2011, he stated he was interested in portraying the drummer from the Who, Keith Moon. From 2013 to 2016, he played the title role in the British television drama series Mr Selfridge, the semi-fictional story based on the life of Harry Selfridge, who founded the London department store Selfridge's. The show aired on the ITV network in the United Kingdom and on PBS in the United States.

On August 1, 2019, Piven appeared on a KTVU morning news segment to promote a standup comedy show he was to perform in the next night in San Francisco.