Hannah Simone

Simone was born in London to an Indian father and a British mother of German, Italian, and Greek Cypriot descent. She has a brother named Zack. Simone spent her early childhood in Calgary, Canada. From ages 7–10, Simone moved through three continents, attending schools in each one. At the age of 13, Simone was living in Cyprus and was working as a fashion model. At 16 years old, Simone lived in New Delhi where she attended the American Embassy School. A year later, at 17, she returned to Canada. Initially settling in White Rock, British Columbia, she subsequently relocated to Vancouver where she attended the University of British Columbia. After her first degree, she returned to Hounslow, United Kingdom for a year, where she worked as a human rights and refugees officer for the United Nations. Following her 2005 graduation from Toronto Metropolitan University, Simone became host of HGTV Canada's television show Space for Living for its first season.

Simone worked at MuchMusic as a VJ at MuchMusic Headquarters, as a news presenter for "Much News Weekly" and, the host of the show The NewMusic. From May 2006 to November 2008, she worked as a VJ for MuchMusic in Canada. She interviewed artists and bands during her time at Much. She then stated that she had plans to move to Los Angeles, California.

Simone hosted WCG Ultimate Gamer alongside Joel Gourdin on Syfy. The series premiered on 10 March 2009 and ended after its second season on 7 October 2010. From 2011 to 2018, Simone appeared in Fox's comedy New Girl.

Alongside Kate Upton and Génesis Rodríguez, she was featured in Gillette's "What Women Want" campaign in 2013.

In 2014, she starred alongside Danny Trejo in Train's music video "Angel in Blue Jeans".

In 2016, she starred in music video "Same Air" from The Rocket Summer. In 2017, she hosted the reality competition television series Kicking & Screaming.

On 12 February 2018, Simone was announced as the lead in ABC's reboot of The Greatest American Hero; however, ABC declined to pick up the series.

She began cohosting Welcome to Our Show, a New Girl rewatch podcast with co-stars Lamorne Morris and Zooey Deschanel, distributed by iHeartRadio, in January 2022.