Diane Ladd

In 1971, Ladd joined the cast of the CBS soap opera The Secret Storm. She was the second actress to play the role of Kitty Styles on the long-running daytime serial. She later had a supporting role in Roman Polanski's 1974 film Chinatown, and was nominated for an Academy Award for Best Actress in a Supporting Role for her role as Flo in the film Alice Doesn't Live Here Anymore. That film inspired the television series Alice, in which Flo was portrayed by Polly Holliday. When Holliday left the TV series, Ladd succeeded her as waitress Isabelle "Belle" Dupree.

Her subsequent film appearances include Black Widow (1987), National Lampoon's Christmas Vacation (1989), Ghosts of Mississippi (1996), Primary Colors (1998), 28 Days (2000), and Joy (2015). She appeared in the independent screwball comedy Hold Me, Thrill Me, Kiss Me in 1992, where she played a flirty, aging Southern belle alongside her real mother, actress Mary Lanier.

In 2004, Ladd played psychic Mrs. Druse in the television miniseries of Stephen King's Kingdom Hospital. In April 2006, Ladd released her first book, Spiraling Through The School of Life: A Mental, Physical, and Spiritual Discovery. In 2007, she co-starred in the Lifetime Television film Montana Sky.

In addition to her Academy Award nomination for Alice Doesn't Live Here Anymore, she was also nominated (again in the Best Actress in a Supporting Role category) for both Wild at Heart and Rambling Rose, both of which she starred alongside her daughter Laura Dern. Dern received a nomination for Best Actress for Rambling Rose. The dual mother and daughter nominations for Ladd and Dern in Rambling Rose marked the first time in Academy Awards history that such an event had occurred. They were also nominated for dual Golden Globe Awards in the same year.

Ladd has also worked in theatre. She made her Broadway debut in Carry Me Back to Morningside Heights in 1968. In 1976, she starred in A Texas Trilogy: Lu Ann Hampton Laverty Oberlander, for which she received a Drama Desk Award nomination.

On November 1, 2010, Ladd, Laura Dern, and Bruce Dern received adjoining stars on the Hollywood Walk of Fame; this is the first time family members have been given such consideration on the Walk. Ladd's star is the 2,421st.

She starred in the Hallmark Channel series Chesapeake Shores.