Diana Muldaur

In 1965, Muldaur landed the role of Ann Wicker in the CBS daytime soap opera The Secret Storm. She then did a five-episode arc as Jeannie Orloff in the final season of Richard Chamberlain's NBC medical drama Dr. Kildare.

Various roles as a guest star in episodes of numerous television shows followed, including Bonanza, I Spy, The Courtship of Eddie's Father, The Invaders, Mannix, Mod Squad, Hawaii Five-O, The F.B.I., The Virginian, a two-episode arc on the Ben Gazzara drama Run for Your Life, and as a guest star in 1975 in S.W.A.T. playing Kate Darby in the episode "Terror Ship".

Collaborations between Muldaur and Burt Reynolds began when Muldaur appeared in an episode of Hawk (1966), a weekly procedural with Reynolds in the title role. Subsequently, they guest-starred in a third-season episode of The F.B.I. (1968), and Muldaur guest-starred in an episode of Reynolds' series Dan August (1970).

In 1967, Muldaur guest-starred on the Gunsmoke episode "Fandango" with James Arness. An excerpt of that episode's dialogue was sampled on the Pink Floyd album The Wall, after "Hey You" and before the brief song "Is There Anybody Out There?"

In 1968, she appeared in the original Star Trek episodes "Return to Tomorrow" as Science Officer Dr. Ann Mulhall, and in "Is There in Truth No Beauty?" as Dr. Miranda Jones. During this time, a friendship with creator Gene Roddenberry formed that led to him casting Muldaur as Marg in the television film Planet Earth (1974) with John Saxon. Later, she appeared as Dr. Katherine Pulaski in 20 episodes of the second season of Star Trek: The Next Generation (1988–1989).

Muldaur's first major role was as Belle in the ABC primetime serial Harold Robbins' The Survivors (1970). The soap, intended as a comeback vehicle for Hollywood star Lana Turner, was cancelled early into the 1970 television season after 15 episodes.