Checco Zalone

Luca Medici was born in Capurso, in the first hinge of the metropolitan area of Bari, close to the suburbs south of the city. The pseudonym Checco Zalone recalls the local expression che cozzalone!, meaning "what a boor!". During his teens, he was very fond of video games and spent most of his afternoons indoors. He graduated from the scientific high school Sante Simone in Conversano; he later enrolled at the University of Bari, where he graduated in law. In the meantime, he participates in the competitions as deputy police inspector and INAIL in Rimini, but is rejected.

After being a regular in many editions of the Canale 5 variety show Zelig, he became famous in 2006 thanks to the song "Siamo una squadra fortissimi" (meaning "we are a very strong team" in broken Italian), celebrating the Italian team just before the 2006 FIFA World Cup. In 2009 he co-wrote and starred in Cado dalle nubi, co-written by Gennaro Nunziante, who also directed.

In 2011, he again co-wrote and starred in Che bella giornata, also co-written and directed by Nunziante. It opened with a record Italian opening weekend of $9.4 million and became the highest-grossing Italian film of all-time in Italy, grossing €43.4 million, surpassing Roberto Benigni's Life Is Beautiful. Life Is Beautiful retained the worldwide record for an Italian film with $70 million worldwide.

In 2013, he and Nunziante followed it up with Sole a catinelle which surpassed it with an opening record of €19.2 million and a total gross of €51.9 million.

In January 2016, his and Nunziante's next film Quo Vado? set another opening weekend record grossing over €22m (£16.5m) over the three-day holiday weekend and went on to become the highest-grossing Italian film of all-time with €65.3 million, second only to Avatar in Italy with €65.7 million. In the same year, Zalone was the Italian testimonial of the funding raising campaign for the research on Spinal muscular atrophy. His and Nunziate's films are currently the second, third, fifth and sixth highest-grossing films in Italy.

On 30 April 2021, Checco Zalone released the video of his song "La vacinada" (meaning "the vaccinated woman" in pseudo-Spanish), starring English actress Helen Mirren. In the song, Zalone jokes about the fact that, in times of Covid-19 pandemic, it is safer to have an affair with someone who has already been vaccinated against the virus, and therefore the best option is a higher-aged partner, as the elderly are the ones who were vaccinated first.

In 2022 he has been guest at Sanremo Music Festival with a medley.